Description

Melanotan II (MT-II) is a synthetic cyclic melanocortin peptide designed as a potent analogue of alpha-melanocyte-stimulating hormone (α-MSH).

It has been researched for melanin production, pigmentation, melanocortin-receptor activity, and sexual-function pathways, making it one of the better-known compounds in melanocortin peptide research.

Product Information
Melanotan II is a cyclic heptapeptide analogue of α-MSH with activity at several melanocortin receptors.

Its strongest recognized biological effect is stimulation of melanogenesis through melanocortin pathways involved in pigmentation. Research has also demonstrated effects on central melanocortin pathways associated with sexual responses.

How Does Melanotan II Work?
Melanotan II activates melanocortin receptors, including MC1R, which stimulates melanin production. Its activity at other melanocortin receptors may also influence central nervous system and sexual function pathways.

Melanotan II Benefits
Stimulates Melanin Production:
Melanotan II was specifically developed to investigate melanocortin-driven pigmentation. In the first human Phase I study, subcutaneous administration produced measurable increases in pigmentation in several participants.

Supports Melanocortin-Receptor Research:
Because MT-II is a potent melanocortin receptor agonist, it provides an important research tool for studying how these receptors influence pigmentation and other physiological processes.

Research Into Sexual-Function Pathways:
The original Phase I study reported spontaneous penile erections following administration, with yawning and stretching appearing to correlate with these responses. These findings helped establish the role of melanocortin signaling in sexual-function research.